Mesothelioma is a type of cancer found in the outer lining of the lungs most commonly diagnosed in people exposed to asbestos. New research shows that some individuals with even minimal asbestos exposure can have a considerably higher chance of developing mesothelioma because they inherited a specific gene mutation.
University of Hawaii cancer researchers understand the tumor suppressing role of the BAP1 gene and discovered that a mutation in the gene prevents proteins from inhibiting tumor formation when cancer is present. The recent study involved administering BAP1 mutated genes into mice then exposing those mice to asbestos. This revealed that BAP1 mice had a higher incidence of mesothelioma after low exposure to asbestos than ordinary mice. The mice that did not receive the mutated BAP1 did not show the inflammatory responses to asbestos that induce mesothelioma.
Although asbestos exposure levels and duration are associated with the risks of developing mesothelioma, University of Hawaii researchers discovered a gene mutation that may identify those at higher risk for developing asbestos related cancers. Gene mutations are hereditary and differences in DNA may contribute to why some people are more susceptible to cancer than others with the same asbestos exposure.
Many people diagnosed with mesothelioma have worked in industries that commonly use asbestos such as construction, insulation and demolition. Not everyone exposed to asbestos develops mesothelioma; however, and current research recognizes the possibility of predisposed genetic connections to cancer regardless of carcinogen exposure.
Testing for the mutated BAP1 gene could prove to be valuable in minimizing the risk of cancer occurrence. Early detection of the gene mutation allows doctors a thorough screening process with frequent exams to help with patient diagnosis and treatment. This type of genetic cancer research can give mesothelioma patients improved prognoses and better survival rates with awareness combined with early intervention.
Philadelphia Asbestos Lawyers at Brookman, Rosenberg, Brown & Sandler Recover Compensation for Mesothelioma Patients
Asbestos related illness and mesothelioma patients endure pain and suffering and long term medical treatment with medical expenses, along with lost wages, which can significantly impact their families. Philadelphia mesothelioma lawyers at Brookman, Rosenberg, Brown & Sandler are committed to negotiate substantial compensation for asbestos exposed victims. Our experienced and knowledgeable asbestos lawyers provide legal guidance in our Center City, Philadelphia offices with free case reviews for mesothelioma clients throughout the Delaware Valley in Pennsylvania and New Jersey. Call 800-369-0899 to discuss your confidential circumstances or submit an online contact inquiry.